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Colonoscopy with Biopsy

Cost of a Colonoscopy with Biopsy Visit:
$287-$932

How much does a colonoscopy with biopsy visit cost? The national median negotiated rate for CPT 45380 is $512, with rates ranging from $287 to $932 across 145,042 providers.

National Median

$512

Low End (P5)

$287

High End (P95)

$932

Providers

145,042

Colonoscopy with Biopsy Visit Costs by State

Click any state to see detailed colonoscopy with biopsy visit pricing. Colors represent the median negotiated rate for CPT 45380.

Median Visit Cost

$287
$932

Colonoscopy with Biopsy Visit Cost by State: All 50 States Ranked

States ranked from lowest to highest median colonoscopy with biopsy visit rate for CPT 45380 (Colonoscopy with biopsy).

RankStateAverage
1Wisconsin
Range: $73$5,357
$385
2New York
Range: $241$2,117
$488
3Massachusetts
Range: $80$2,117
$600
4Rhode Island
Range: $80$2,117
$535
5Connecticut
Range: $85$2,117
$475
6Delaware
Range: $80$2,117
$376
7Pennsylvania
Range: $80$2,117
$373
8Minnesota
Range: $85$1,970
$504
9New Hampshire
Range: $433$1,234
$819
10Nebraska
Range: $281$1,040
$904
11Iowa
Range: $85$1,373
$720
12California
Range: $80$1,785
$308
13Maine
Range: $456$887
$799
14Wyoming
Range: $217$1,313
$442
15Vermont
Range: $317$1,042
$537
16Georgia
Range: $85$1,250
$525
17New Jersey
Range: $120$1,329
$349
18North Carolina
Range: $80$1,268
$444
19North Dakota
Range: $80$1,268
$434
20District of Columbia
Range: $98$1,143
$498
21West Virginia
Range: $85$1,329
$308
22New Mexico
Range: $90$1,136
$451
23Illinois
Range: $80$1,147
$441
24Washington
Range: $80$1,143
$385
25Utah
Range: $80$944
$537
26Missouri
Range: $188$815
$534
27South Dakota
Range: $80$1,035
$389
28Maryland
Range: $175$919
$373
29Oregon
Range: $80$1,070
$308
30Hawaii
Range: $80$969
$351
31Colorado
Range: $85$969
$344
32Indiana
Range: $80$937
$365
33Mississippi
Range: $162$850
$349
34Michigan
Range: $80$887
$393
35Kentucky
Range: $80$917
$322
36Virginia
Range: $98$830
$343
37Louisiana
Range: $85$804
$376
38Idaho
Range: $80$906
$272
39Arkansas
Range: $85$815
$349
40Alabama
Range: $80$762
$372
41Texas
Range: $85$772
$332
42South Carolina
Range: $80$782
$306
43Kansas
Range: $188$646
$328
44Nevada
Range: $85$701
$331
45Ohio
Range: $85$709
$319
46Tennessee
Range: $85$714
$314
47Alaska
Range: $80$837
$80
48Arizona
Range: $85$567
$233
49Florida
Range: $35$770
$55
50Oklahoma
Range: $85$582
$85
51Montana
Range: $80$545
$80

Frequently Asked Questions

How much does a colonoscopy with biopsy cost without insurance?

The average negotiated rate for a colonoscopy with biopsy (CPT 45380) is $577 nationally. Rates typically range from $287 to $932 depending on your state and provider. Without insurance, you may pay the provider's full charge rate, which can be 2-3x higher than negotiated rates.

How much does a colonoscopy with biopsy cost with insurance?

With insurance, your out-of-pocket cost for a colonoscopy with biopsy depends on your plan's copay, coinsurance, and whether you've met your deductible. The average insurer-negotiated rate is $577. Most plans charge a specialist copay of $30-$75, or you may owe a percentage (typically 20-30%) after your deductible is met.

Why do colonoscopy with biopsy costs vary by state?

Healthcare costs vary significantly by state due to differences in cost of living, provider supply and demand, state regulations, and negotiated rates between insurers and providers. Urban areas and states with higher costs of living (like New York and California) tend to have higher rates.

What does CPT code 45380 cover?

CPT 45380 is the billing code for: Colonoscopy with biopsy. This is one of the standard codes used when billing for this procedure.

What factors affect the cost of a colonoscopy with biopsy?

Several factors influence the cost: (1) Your geographic location — rates vary 2-3x between states, (2) Whether you have insurance and which plan, (3) Whether the provider is in-network, (4) The complexity of your case, (5) The facility where the procedure is performed.

Get Your Personalized Cost Estimate

These are the negotiated rates providers across the US are contracted to accept. Your personal share depends on your deductible and coinsurance. Call your insurer's member line with CPT code 45380 to get your exact estimate or talk to our AI to get your answers.

Written by Jayant Panwar | Last reviewed: Q1 2026

Rates sourced from Transparency in Coverage machine-readable files (Q1 2026). Negotiated rates are contracted prices between insurers and individual providers and do not represent guaranteed patient out-of-pocket costs. Actual costs depend on insurance plan terms, deductible status, coinsurance rate, and specific services received.